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Get better batch-to-batch reproducibility with a recombinant antibody
Anti-G-protein coupled receptor 30 antibody [EPR23701-79] (ab260033)
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-G-protein coupled receptor 30 antibody - N-terminal
See all G-protein coupled receptor 30 primary antibodies -
Description
Rabbit polyclonal to G-protein coupled receptor 30 - N-terminal
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Host species
Rabbit
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Specificity
BLAST analysis of the peptide immunogen showed no hom*ology with other Human proteins.
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Tested applications
Suitable for: IHC-Pmore details
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Species reactivity
Reacts with: Human
Predicted to work with: Monkey, Gorilla, Common marmoset -
Immunogen
Synthetic peptide corresponding to Human G-protein coupled receptor 30 (N terminal). (16 amino acid peptide from the N terminal extracellular domain; NP_001496.1).
Database link: Q99527 -
Positive control
- Human breast carcinoma tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid
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Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
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Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified
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Clonality
Polyclonal
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Isotype
IgG
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Research areas
- Neuroscience
- Neurotransmission
- Receptors / Channels
- GPCR
- More GPCR
- Signal Transduction
- Signaling Pathway
- G Protein Signaling
- GPCR
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Estrogen
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
- Metabolism
- Pathways and Processes
- Endocrine metabolism
- Hormone biosynthesis
Associated products
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Compatible Secondaries
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Isotype control
- Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
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Recombinant Protein
- Recombinant Human G-protein coupled receptor 30 (ab152434)
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab188999 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P | Use a concentration of 20 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Notes |
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IHC-P |
Target
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Function
Receptor for estrogen.
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Tissue specificity
Ubiquitously expressed, but is most abundant in placenta. In brain regions, expressed as a 2.8 kb transcript in basal forebrain, frontal cortex, thalamus, hippocampus, caudate and putamen.
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Sequence similarities
Belongs to the G-protein coupled receptor 1 family.
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Cellular localization
Cell membrane. Endoplasmic reticulum membrane. Golgi apparatus membrane. Protein has been detected in the cell membrane, endoplasmic reticulum and Golgi apparatus. It is currently unclear whether this is a cell surface or intracellular receptor.
- Information by UniProt
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Database links
- Entrez Gene: 2852 Human
- Omim: 601805 Human
- SwissProt: Q99527 Human
- Unigene: 20961 Human
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Alternative names
- CEPR antibody
- Chemoattractant receptor-like 2 antibody
- Chemokine receptor-like 2 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-G-protein coupled receptor 30 antibody - N-terminal (ab188999)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human breast carcinoma tissue labeling G-protein coupled receptor 30 with ab188999 at 20 µg/ml.
Datasheets and documents
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SDS download
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Datasheet download
Download
References (2)
Publishing research using ab188999? Please let us know so that we can cite the reference in this datasheet.
ab188999 has been referenced in 2 publications.
- Lee S et al. Estrogen Aggravates Tumor Growth in a Diffuse Gastric Cancer Xenograft Model. Pathol Oncol Res 27:622733 (2021). PubMed: 34257587
- Kim KM & Jung J Upregulation of G Protein-Coupled Estrogen Receptor by Chrysin-Nanoparticles Inhibits Tumor Proliferation and Metastasis in Triple Negative Breast Cancer Xenograft Model. Front Endocrinol (Lausanne) 11:560605 (2020). PubMed: 33042020